CM : Cutaneous Melanoma.

NA : no data provided, or published OR (Odds Ratio) used, or in case of overlap, data included in original study.

Source : "CL" (clinic-based), "PO" (population-based), "NHS" (Nurses Health Study), "HPFS" (Health Professionals Follow-up Study).

Design : "CC" (case-control), "FBAT" (Family-Based Study).

Association with Melanoma: Overall conclusion reached by authors of the original publication ("P" indicates significant (P < 0.05) association in at least one of the performed analyses, and "NS" indicates non - significant association); results obtained in duplicate or largely overlapping samples are listed as "NA".

Genotypes in cases and controls

M/M: Major / Major

M/m: Major / minor

m/m: minor / minor

Top Melgene Results

Gene 1: CLPTM1L

Gene 2: TYRP1

Gene 3: MTAP

Gene 4: CDKN2A

Gene 5: OCA2

Gene 6: MYH7B

Gene 7: SLC45A2

Gene 8: PLA2G6

Gene 9: MX2

Gene 10: VDR

Gene 11: FTO

Gene 12: CCND1

Gene 13: MITF

Gene 14: TYR

Gene 15: CDK10

Gene 16: AFG3L1

Gene 17: XPG

Gene 18: ATM

Gene 19: CASP8

Gene 20: PARP1

MelGene Statistics





How to Cite

1. Emmanouil Athanasiadis, Antonopoulou Kyriaki, Chatzinasiou Foteini, Christina Lill, Marilena Bourdakou, Argiris Sakellariou, Katerina Kypreou, Irene Stefanaki, Evangelos Evangelou, John Ioannidis, Lars Bertram, Alexander Stratigos and George Spyrou. (2014) A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database, Vol. 2014: article ID bau101; doi:10.1093/database/bau101.

2. Kyriaki Antonopoulou, Irene Stefanaki, Christina M Lill, Foteini Chatzinasiou, Katerina Kypreou, Fani Karagianni, Emmanouil Athanasiadis, George M Spyrou, John P A Ioannidis, Lars Bertram, Evangelos Evangelou and Alexander J Stratigos. (2014) Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene Database, J Invest Dermatol, doi:10.1038/jid.2014.491 .

3. Foteini Chatzinasiou, Christina M. Lill, Katerina Kypreou, Irene Stefanaki, Vasiliki Nicolaou, George Spyrou, Evangelos Evangelou, Johannes T. Roehr, Elizabeth Kodela, Andreas Katsambas, Hensin Tsao, John P.A. Ioannidis, Lars Bertram, Alexander J. Stratigos. (2011) Comprehensive Field Synopsis and Systematic Meta-analyses of Genetic Association Studies in Cutaneous Melanoma, J Natl Cancer Inst 103:1-9.