Polymorphism:
rs1042602 (S192Y)

Meta-Analysis Plots

meta-analysis of the log odd ratios using random-effects models

some textClick forest plot to enlarge


Contour-enhanced funnel plot of the log odd rations vs standard error

some textClick funnel plot to enlarge

Meta-Analysis Details


StudyPopulationSourceGeneChromosomePolymorphismResultComments
Gudbjartsson, Nat Genet, 2008IcelandPOTYR11rs1042602 (S192Y)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
8100.27CA42232563367230.29918046153943283

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Gudbjartsson, Nat Genet, 2008SwedenCL cases / blood donors controls TYR11rs1042602 (S192Y)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
10330.30CA4994389626480.30312861119243

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Gudbjartsson, Nat Genet, 2008SpainCL TYR11rs1042602 (S192Y)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
2680.43CA851325112280.453367609252

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Fernandez, Hum Mutat, 2008SpainCLTYR11rs1042602 (S192Y)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1310.46CA3865282450.4696912254

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Council, Exp Dermatol, 2009USACLTYR11rs1042602 (S192Y)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1380.39CA5166213560.38513516853

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Nan, Int J Cancer, 2009USANHSTYR11rs1042602 (S192Y)NSAdjusted for age.
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
2090.38CA8098318360.34735238896

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Bishop, Nat Genet, 2009Genome-wide phase_ Australia, UK, France, Italy, Spain, Sweden.POTYR11rs1042602 (S192Y)NS1,13x10-1 OR 0,93 CI(0,85-1,02)
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1539NACANANANA3917NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Bishop, Nat Genet, 2009Replication GenoMEL (REP1)POTYR11rs1042602 (S192Y)P0,097 OR 0,89 CI(0,78-1,02)
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1149NACANANANA964NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Bishop, Nat Genet, 2009Replication Leeds (REP2)POTYR11rs1042602 (S192Y)NS0,27 OR 0,93 CI(0,82-1,06)
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1163NACANANANA903NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Duffy, J Invest Dermatol, 2010AustraliaPOTYR11rs1042602 (S192Y)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
17280.33CA75577419941120.34917451867500