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Polymorphism:
rs1126809 (R402Q)

Meta-Analysis Plots

meta-analysis of the log odd ratios using random-effects models

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Contour-enhanced funnel plot of the log odd rations vs standard error

some textClick funnel plot to enlarge

Meta-Analysis Details


StudyPopulationSourceGeneChromosomePolymorphismResultComments
Gudbjartsson, Nat Genet, 2008IcelandPOTYR11rs1126809 (R402Q)PNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
8100.32GA36635787367230.30117943154533327

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Gudbjartsson, Nat Genet, 2008SwedenCL cases / blood donors controls TYR11rs1126809 (R402Q)PNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
10330.31GA49044310026480.25514701006172

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Gudbjartsson, Nat Genet, 2008SpainCL TYR11rs1126809 (R402Q)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
2680.28GA1361102212280.2667247383

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Fernandez, Hum Mutat, 2008SpainCLTYR11rs1126809 (R402Q)NANA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
131NAGANANANA245NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Council, Exp Dermatol, 2009USACLTYR11rs1126809 (R402Q)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1370.29GA685712NANANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Bishop, Nat Genet, 2009Genome-wide phase_ Australia, UK, France, Italy, Spain, Sweden.POTYR11rs1126809 (R402Q)NANA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1539NAGANANANA3917NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Bishop, Nat Genet, 2009Replication GenoMEL (REP1)POTYR11rs1126809 (R402Q)P7,16xe-05 OR 1,34 CI(1,16-1,54)
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1149NAGANANANA964NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Bishop, Nat Genet, 2009Replication Leeds (REP2)POTYR11rs1126809 (R402Q)P3,19xe-03 OR 1,22 CI(1,07-1,40)
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
1163NAGANANANA903NANANANA

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Duffy, J Invest Dermatol, 2010AustraliaPOTYR11rs1126809 (R402Q)PNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
17310.35GA73178821241020.30619751743384

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Hu, J Dermatol Sci, 2011 FranceCLTYR11rs1126809 (R402Q)PNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
10470.30GA5114351019250.27947039461

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Helsing, Genes Chromosomes Cancer, 2012NorwayPOTYR11rs1126809 (R402Q)NSNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
3850.29GA187171274150.27521716830

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Ibarrola-Villava, Eur J Cancer, 2012France, Italy, SpainCLTYR11rs1126809 (R402Q)PNA
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
11720.29GA58447511311580.27559948277

StudyPopulationSourceGeneChromosomePolymorphismResultComments
Stefanaki, Plos One, 2013GreeceCLTYR11rs1126809 (R402Q)ns1,19[0,88-1,62]
CasesControls
NumberMinor Allele FrequencyMajor AlleleMinor AlleleM/MM/mm/mNumberMinor Allele FrequencyM/MM/mm/m
284GANANANA284NANANA

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