Welcome to MelGene (version 2.0)

The MelGene database provides a comprehensive and regularly updated field synopsis and meta-analysis of all published genetic association studies performed in Cutaneous Melanoma (CM).

In addition, dozens of up-to-date meta-analyses are available for all eligible polymorphisms with sufficient data. For details, see Methods.

Alternative access to the Database can be performed via the mirror site:.
http://bioserver-3.bioacademy.gr/Bioserver/MelGene/.

CHROMOSOMAL LOCATION OF PUBLISHED CANDIDATE CM LOCI/GENES
The chromosome graphics are used after written permission from the Map Viewer, Genome Database, National Center for Biotechnology Information, US National Library of Medicine.

Top Melgene Results

Gene 1: CLPTM1L

Gene 2: TYRP1

Gene 3: MTAP

Gene 4: CDKN2A

Gene 5: OCA2

Gene 6: MYH7B

Gene 7: SLC45A2

Gene 8: PLA2G6

Gene 9: MX2

Gene 10: VDR

Gene 11: FTO

Gene 12: CCND1

Gene 13: MITF

Gene 14: TYR

Gene 15: CDK10

Gene 16: AFG3L1

Gene 17: XPG

Gene 18: ATM

Gene 19: CASP8

Gene 20: PARP1

MelGene Statistics

Studies
192

Genes
280

Polymorphisms
1,114

Meta-analyses
79

How to Cite

1. Emmanouil Athanasiadis, Antonopoulou Kyriaki, Chatzinasiou Foteini, Christina Lill, Marilena Bourdakou, Argiris Sakellariou, Katerina Kypreou, Irene Stefanaki, Evangelos Evangelou, John Ioannidis, Lars Bertram, Alexander Stratigos and George Spyrou. (2014) A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database, Vol. 2014: article ID bau101; doi:10.1093/database/bau101.

2. Kyriaki Antonopoulou, Irene Stefanaki, Christina M Lill, Foteini Chatzinasiou, Katerina Kypreou, Fani Karagianni, Emmanouil Athanasiadis, George M Spyrou, John P A Ioannidis, Lars Bertram, Evangelos Evangelou and Alexander J Stratigos. (2014) Updated Field Synopsis and Systematic Meta-Analyses of Genetic Association Studies in Cutaneous Melanoma: The MelGene Database, J Invest Dermatol, doi:10.1038/jid.2014.491 .

3. Foteini Chatzinasiou, Christina M. Lill, Katerina Kypreou, Irene Stefanaki, Vasiliki Nicolaou, George Spyrou, Evangelos Evangelou, Johannes T. Roehr, Elizabeth Kodela, Andreas Katsambas, Hensin Tsao, John P.A. Ioannidis, Lars Bertram, Alexander J. Stratigos. (2011) Comprehensive Field Synopsis and Systematic Meta-analyses of Genetic Association Studies in Cutaneous Melanoma, J Natl Cancer Inst 103:1-9.