I
G
R E N E -
Platform
HOME PAGE
I
G
RENE -
DON
I
G
RENE -
DIN
I
G
RENE -
GIN
DOCUMENTATION
Integrating Gene Regulatory Networks - Drug Influence Networks
Pick-up an example
DRUGBANK - Farnesyl diphosphate drug towards KRAS modulation
DRUGBANK - RU79256 drug towards KRAS modulation
DRUGBANK - Cetuximab drug towards KRAS modulation
DRUGBANK - Bevacizumab drug towards KRAS modulation
DRUGBANK - Lenvatinib drug towards KRAS modulation
DRUGBANK - Pembrolizumab drug towards KRAS modulation
DRUGBANK - Olokizumab drug towards IL6 modulation
DRUGBANK - Dimethyl fumarate drug towards IL6 modulation
DRUGBANK - Andrographolide drug towards IL6 modulation
CREEDS - Resveratrol drug towards KRAS modulation
Select Reference Network
info
Use Signor Drug Repository
Use Drugbank Drug Repository
Use Gene-Budger L1000 Repository
-->
Use Gene-Budger CREEDS Drug Repository
-->
Use Gene-Budger CMAP Repository
Select Network Level
info
Auto Detect Level
2
nd
Network Level
3
rd
Network Level
4
th
Network Level
5
th
Network Level
Select the drug of interest
info
Select the gene of interest
info
Go for it
Investigate both the activation and suppression networks stemming from a candidate drug to a specific target gene