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DOCUMENTATION
Integrating Gene Regulatory Networks - Gene Influence Networks
Pick-up an example
SIGNOR - TP53 towards KRAS modulation
SIGNOR - EGFR towards KRAS modulation
SIGNOR - VEGFA towards KRAS modulation
SIGNOR - IL6R towards IL6 modulation
Use Signor Drug Repository
Use Drugbank Drug Repository (approved)
Use Drugbank Drug Repository (Other Types)
Use Gene-Budger L1000 Repository
Use Gene-Budger CREEDS Drug Repository
Use Gene-Budger CMAP Repository
Select Network Level
info
Auto Detect Level
2
nd
Network Level
3
rd
Network Level
4
th
Network Level
5
th
Network Level
I want to suppress
I want to activate
Select the source gene
info
Select the target gene
info
Go for it
Investigate both the activation and suppression networks stemming from a source gene to a specific target gene